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Butamirate

CAT: 0804-HY-118545-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-118545-01Size:5 mg
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Description
Butamirate is an orally active antitussive agent that acts centrally through the receptors in the brainstem. Butamirate also reduces the resistance in the airways by inhibiting bronchospasm and anti-inflammatory effect. Butamirate inhibits glioblastoma (GBM) growth and STAT3 activity. Butamirate can be used for the study of glioblastoma[1][2].
CAS Number
18109-80-3
Product Name Alternative
CS-505
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/butamirate.html
Concentration
10mM
Purity
96.48
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C(C(C1=CC=CC=C1)CC)OCCOCCN(CC)CC
Molecular Formula
C18H29NO3
Molecular Weight
307.43
References & Citations
[1]Płusa T. et al. Butamirate citrate in control of cough in respiratory tract inflammation. Pol Merkur Lekarski. 2017 Aug 21;43 (254) :69-74.|[2]Lee SJ, et al. Application of the antitussive agents oxelaidin and butamirate as anti-glioma agents. Sci Rep. 2021 May 12;11 (1) :10145.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1

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