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Casimersen (sodium)

CAT: 0804-HY-132584A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-132584A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
SRP-4045 (sodium)
UNSPSC Description
Casimersen sodium is an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer subclass. Casimersen sodium binds to exon 45 of dystrophin pre-mRNA, restores the open-reading frame (by skipping exon 45) resulting in the production of an internally truncated but functional dystrophin protein. Casimersen sodium can be used for the research of Duchenne muscular dystrophy (DMD)[1].
Target Antigen
Others
Type
Oligonucleotides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/casimersen-sodium.html
Purity
99.07
Solubility
H2O : ≥ 25 mg/mL
Smiles
[Casimersen(sodium)]
Molecular Weight
8068.01
References & Citations
[1]Shirley M. Casimersen: First Approval. Drugs. 2021;81(7):875-879. |[2]Casimersen. Am J Health Syst Pharm. 2021;78(13):1149-1150. |[3]Carver MP, Charleston JS, Shanks C, et al. Toxicological Characterization of Exon Skipping Phosphorodiamidate Morpholino Oligomers (PMOs) in Non-human Primates. J Neuromuscul Dis. 2016;3(3):381-393. doi:10.3233/JND-160157
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen, away from moisture)
Clinical Information
Phase 3

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