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Human FGFR3 Protein, His Tag

CAT: 0013-GTR18917871-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18917871-01Size:10 µg
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Description
Recombinant human FGFR3 protein with C-terminal 6xHis tag
Product Name Alternative
ACH; CD333; CEK2; HSFGFR3EX; JTK4
UniProt
P22607
Expression Region
FGFR3 (Glu23-Gly375) 6xHis tag
Reactivity
Human
Conjugation
Unconjugated
Tag
C-6xHis Tag
Source
Mammalian
Field of Research
Cell Biology
Purity
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
Form
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Molecular Weight
The protein has a predicted molecular mass of 39.0 kDa after removal of the signal peptide. The apparent molecular mass of FGFR3-His is approximately 55-70 kDa due to glycosylation.
Storage Conditions
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.
Notes
For research use only.
Preservative
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.

UniProtKB · P22607

Fibroblast growth factor receptor 3

FGFR3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P22607
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
FGFR3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
FGFR-3
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
D3DVP9, D3DVQ0, Q14308, Q16294, Q16608, Q59FL9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

Apoptosis

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumMembraneSecreted

Disease

CraniosynostosisDeafnessDisease variantDwarfismEctodermal dysplasiaLacrimo-auriculo-dento-digital syndrome

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

Molecular function

KinaseReceptorTransferaseTyrosine-protein kinase

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