CP-868388 (free base)

CP-868388 (free base)

• CAS Number: 702681-67-2
• UNSPSC Description: CP-868388 free base is a potent, selective and orally active PPARα agonist with a Ki value of 10.8 nM. CP-868388 free base has little or no affinity for PPARβ (Ki of 3.47 μM) and PPARγ. CP-868388 free base has hypolipidemic and anti-inflammatory actions[1].
• Target Antigen: PPAR
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor
• Field of Research: Metabolic Disease; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/cp-868388-free-base.html
• Purity: 99.84
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: O=C(N1C[C@H](C2=CC=CC(OC(C)(C(O)=O)C)=C2)CCC1)OCC3=CC=C(C(C)C)C=C3
• Molecular Weight: 439.54
• References & Citations: [1]Christopher D Kane, et al. Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo. Mol Pharmacol. 2009 Feb;75(2):296-306.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported