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Noggin Recombinant Protein

CAT: 0013-GTR18911731-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18911731-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Noggin Recombinant Protein
Product Name Alternative
SYM1, SYNS1, Noggin
UniProt
Q13253
Source
HEK293 cells
Field of Research
Cancer Biology, Cell Biology, Signal Transduction
Purity
Greater than 95% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Biological activity was determined by its ability to inhibit 5.0 ng/mL of BMP - 4 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is 2.0 - 3.0 ng/mL of Noggin.
Form
Lyophilized
Storage Conditions
The lyophilized Noggin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Noggin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Noggin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_005441.1
AA Sequence
QHYLHIRPAP SDNLPLVDLI EHPDPIFDPK EKDLNETLLR SLLGGHYDPG FMATSPPEDR PGGGGGAAGG AEDLAELDQL LRQRPSGAMP SEIKGLEFSE GLAQGKKQRL SKKLRRKLQM WLWSQTFCPV LYAWNDLGSR FWPRYVKVGS CFSKRSCSVP EGMVCKPSKS VHLTVLRWRC QRRGGQRCGW IPIQYPIISE CKCSC

UniProtKB · Q13253

Noggin

NOGG_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13253
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NOG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
—
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

ChondrogenesisDifferentiation

Disease

DeafnessDisease variant

Molecular function

Developmental protein

PTM

Disulfide bondGlycoprotein

Cellular component

Secreted

Domain

Signal

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