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NGF beta Recombinant Protein

CAT: 0013-GTR18909541-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18909541-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NGF beta Recombinant Protein
Product Name Alternative
NGFB, HSAN5, Beta-NGF, NGFB, Beta-nerve growth factor
UniProt
P01138
Source
E. coli
Field of Research
Neuroscience
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg) .
Bioactivity
Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Form
Lyophilized
Storage Conditions
The lyophilized NGF beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NGF beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing NGF beta recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Notes
For research use only.
NCBI Accession Number
NP_002497.2
AA Sequence
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR

UniProtKB · P01138

Beta-nerve growth factor

NGF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01138
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NGF
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Beta-NGF
EC number
—
Processing
Precursor
Secondary accessions
A1A4E5, Q6FHA0, Q96P60, Q9P2Q8, Q9UKL8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Disease

Disease variantNeurodegenerationNeuropathy

Cellular component

EndosomeSecreted

Molecular function

Growth factorMetalloenzyme inhibitorMetalloprotease inhibitorProtease inhibitor

Ligand

Lipid-binding

Domain

Signal

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