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Flagellin Recombinant Protein

CAT: 0013-GTR18909038Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18909038Size:100 µg
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Description
Flagellin Recombinant Protein
Product Name Alternative
FliC
UniProt
P60568
Source
Salmonella typhimurium strain 14028
Concentration
1 mg/ml after reconstitution.
Purity
>90% (SDS-PAGE) . Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza) .
Bioactivity
Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin (MMP-7) . Maturation of dendritic cells in in vitro and in vivo assays. Adjuvant activity on foreign antigens delivered by subcutaneous and intranasal routes in mice. TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1ug /mouse.
Form
Lyophilized
Storage Conditions
Stable for at least 6 months after receipt when stored at -20°C.
Notes
For research use only.
Applications Notes
This recombinant proteins is for research use only.
NCBI Accession Number
P06179
Preservative
Contains PBS. Reconstitute with 100 μl sterile water.

UniProtKB · P60568

Interleukin-2

IL2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P60568
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
IL2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
IL-2
EC number
—
Processing
Precursor
Secondary accessions
P01585
Protein keywords

Technical term

3D-structureDirect protein sequencingPharmaceuticalProteomics identificationReference proteome

Biological process

Adaptive immunityImmunity

Coding sequence diversity

Chromosomal rearrangement

Molecular function

CytokineGrowth factor

PTM

Disulfide bondGlycoprotein

Disease

Proto-oncogene

Cellular component

Secreted

Domain

Signal

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