Sigma-LIGAND-1 (hydrochloride)

• UNSPSC Description:

  Sigma-LIGAND-1 hydrochloride is a selective sigma receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 hydrochloride has a Ki of 4000 nM at the dopamine D2 receptor[1].

• Target Antigen:

  Sigma Receptor

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/sigma-ligand-1-hydrochloride.html

• Purity:

  99.13

• Solubility:

  DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1C(C)=C(C2=CC=CC=C2)OC3=CC=C(OCCCCCCN4CCC(O)CC4)C=C13.[H]Cl

• Molecular Weight:

  472.02

• References & Citations:

  [1]Erickson RH, et al. (Aminoalkoxy)chromones. Selective sigma receptor ligands. J Med Chem. 1992 May 1;35(9):1526-35.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported

• CAS Number:

  139652-86-1