cIAP1 Ligand-Linker Conjugates 15 (hydrochloride)

• Product Name Alternative:

  E3 ligase Ligand-Linker Conjugates 34 (hydrochloride)

• UNSPSC Description:

  cIAP1 Ligand-Linker Conjugates 15 hydrochloride incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 15 hydrochloride can be used to design SNIPERs[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e3-ligase-ligand-linker-conjugates-34-hydrochloride.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NCCOCCOCCOC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC1=CC=CC=C1)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O.Cl

• Molecular Weight:

  698.25

• References & Citations:

  [1]Itoh Y, et al. Protein knockdown using methyl bestatin-ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins. J Am Chem Soc. 2010 Apr 28;132(16):5820-6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1225383-36-7