Importazole

• UNSPSC Description:

  Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.

• Target Antigen:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Importazole.html

• Purity:

  99.99

• Solubility:

  DMSO : ≥ 33 mg/mL

• Smiles:

  CC(NC1=C2C=CC=CC2=NC(N3CCCC3)=N1)C4=CC=CC=C4

• Molecular Weight:

  318.42

• References & Citations:

  [1]Soderholm JF, et al. Importazole, a small molecule inhibitor of the transport receptor importin-β. ACS Chem Biol. 2011 Jul 15;6(7):700-8.|[2]Yan WQ, et al. Effect of nuclear receptor inhibitor importazole on the proliferation and apoptosis of multiple myeloma cells. Zhonghua Xue Ye Xue Za Zhi. 2013 Apr;34(4):323-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  662163-81-7