Importazole

• Description :

  Importazole is a small molecule inhibitor of the nuclear transport receptor importin-β.

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis

• Type :

  Reference compound

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Importazole.html

• Purity :

  99.99

• Solubility :

  DMSO : ≥ 33 mg/mL

• Smiles :

  CC(NC1=C2C=CC=CC2=NC(N3CCCC3)=N1)C4=CC=CC=C4

• Molecular Formula :

  C20H22N4

• Molecular Weight :

  318.42

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Soderholm JF, et al. Importazole, a small molecule inhibitor of the transport receptor importin-β. ACS Chem Biol. 2011 Jul 15;6 (7) :700-8.|[2]Yan WQ, et al. Effect of nuclear receptor inhibitor importazole on the proliferation and apoptosis of multiple myeloma cells. Zhonghua Xue Ye Xue Za Zhi. 2013 Apr;34 (4) :323-6.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [662163-81-7]