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CD40 Ligand Recombinant Protein

CAT: 0013-GTR18908779Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18908779Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CD40 Ligand Recombinant Protein
Product Name Alternative
CD40 Ligand, CD40-L, T-Cell Antigen Gp39, TNF-Related Activation Protein, TRAP, Tumor Necrosis Factor Ligand Superfamily Member 5, CD154, CD40LG, CD40L, TNFSF5
UniProt
P29965
Tag
Tag Free
Source
E. coli
Field of Research
Immunology & Inflammation
Purity
Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Bioactivity
Recombinant CD40L is fully biologically active when compared to standards.ED50 is 5-10 ng/ml as determined by the dose-dependent stimulation of IL-12 & IL-8 induction by PMB (Peripheral Mononuclear) cells.
Form
Lyophilized
Molecular Weight
16.2 kD
Storage Conditions
Lyophilized protein should be stored at -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at -20°C for 3 months.
Notes
For research use only.
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Accession Number
P29965
Preservative
Lyophilized from a 0.2 um filtered solution of 20mM PB, 200mM NaCl, 0.1mM EDTA, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
AA Sequence
Met113-Leu261

UniProtKB · P29965

CD40 ligand

CD40L_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P29965
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD40LG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
CD40-L
EC number
—
Processing
—
Secondary accessions
—
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cell membraneMembraneSecreted

Molecular function

Cytokine

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Domain

Signal-anchorTransmembraneTransmembrane helix

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