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C3a [Trp63, 64] peptide

CAT: 0013-GTR18899430-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18899430-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C3a [Trp63, 64] peptide
Source
Synthetic
Field of Research
Cell Biology
Purity
> 95%
Form
Lyophilized powder
Molecular Weight
1820.19
Storage Conditions
Shipped at 4°C. Store at -20°C for one year.
Notes
For research use only.
Applications Notes
[Trp63, 64]-C3a (63-77), synthetic superagonist analog of complement 3a, exhibited the greatest biological potency of all peptides tested. The peptide was 12-15 times more active than natural C3a. Such an optimal potency was obtained by introducing a bulky hydrophobic group such as Trp-Trp which binds more strongly to the hydrophobic site on the receptor than does the corresponding site on the natural ligand.
AA Sequence
Trp-Trp-Gly-Lys-Lys-Tyr-Arg-Ala-Ser-Lys-Leu-Gly-Leu-Ala-Arg

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