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MPT0B390

CAT: 0804-HY-145426-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-145426-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM[1].
CAS Number
1817802-18-8
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mpt0b390.html
Purity
98.76
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NO)/C=C/C1=CN=C(N(S(=O)(C2=CC=C(OC)C=C2)=O)CC3)C3=C1
Molecular Formula
C17H17N3O5S
Molecular Weight
375.40
References & Citations
[1]Han-Li Huang, et al. TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis. Theranostics. 2019 Sep 18;9 (22) :6676-6689.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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