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Human IL4R protein

CAT: 0013-GTR18885443-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18885443-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human IL4R protein spans the amino acid sequence from region 26-231aa. Purity: Greater than 95% as determined by SDS-PAGE.
Product Name Alternative
Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD124; IL-4-binding protein; IL4-BP; IL4R; IL4RA
UniProt
P24394
Expression Region
26-231aa
Tag
C-terminal Fc-tagged
Source
Mammalian cell
Origin
Homo sapiens (Human)
Field of Research
Immunology & Inflammation
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
Greater than 95% as determined by SDS-PAGE.
Bioactivity
1The ED50 as determined by its ability to inhibit IL-4-dependent proliferation of TF‐1 human erythroleukemic cells is 5-20 ng/ml.2Measured by its binding ability in a functional ELISA. Immobilized Human IL-4 RA-Fc at 5μg/ml can bind Human IL-4 (Biotinylated by NHS-biotin prior to testing), the ED50 of Human IL-4 is 2.43 ng/ml.
Form
Lyophilized powder
Molecular Weight
50.2 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Extracellular Domain
Preservative
Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
AA Sequence
MKVLQEPTCVSDYMSISTCEWKMNGPTNCSTELRLLYQLVFLLSEAHTCIPENNGGAGCVCHLLMDDVVSADNYTLDLWAGQQLLWKGSFKPSEHVKPRAPGNLTVHTNVSDTLLLTWSNPYPPDNYLYNHLTYAVNIWSENDPADFRIYNVTYLEPSLRIAASTLKSGISYRARVRAWAQCYNTTWSEWSPSTKWHNSYREPFEQ

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