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Human NKX2-1 protein

CAT: 0013-GTR18886647-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18886647-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human NKX2-1 protein spans the amino acid sequence from region 1-371aa. Purity: Greater than 85% as determined by SDS-PAGE.
Product Name Alternative
Homeobox protein NK-2 homolog A (Thyroid nuclear factor 1) (Thyroid transcription factor 1) (TTF-1) (Thyroid-specific enhancer-binding protein) (T/EBP) (NKX2A) (TITF1) (TTF1)
UniProt
P43699
Expression Region
1-371aa
Tag
N-terminal 10xHis-tagged and C-terminal Myc-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Epigenetics & Chromatin
Purity
Greater than 85% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
46.0 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Full Length
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
MSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLGAPLAAYRQGQAAPPTAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNMSELPPYQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQLQQDSGGGGGGGGTGCPQQQQAQQQSPRRVAVPVLVKDGKPCQAGAPAPGAASLQGHAQQQAQHQAQAAQAAAAAISVGSGGAGLGAHPGHQPGSAGQSPDLAHHAASPAALQGQVSSLSHLNSSGSDYGTMSCSTLLYGRTW

UniProtKB · P43699

Homeobox protein Nkx-2.1

NKX21_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P43699
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NKX2-1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D3DSA3, O14954, O14955, Q7KZF6, Q9BRJ8
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

Coding sequence diversity

Alternative splicing

Biological process

Biological rhythmsTranscriptionTranscription regulation

Disease

Congenital hypothyroidismDisease variant

Domain

Homeobox

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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