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Baloxavir

CAT: 0804-HY-109025A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-109025A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Baloxavir (Baloxavir acid), derived from the proagent Baloxavir marboxil, is a first-in-class, potent and selective cap-dependent endonuclease (CEN) inhibitor within the polymerase PA subunit of influenza A and B viruses. Baloxavir inhibits viral RNA transcription and replication and has potently antiviral activity[1][2].
CAS Number
1985605-59-1
Product Name Alternative
Baloxavir acid; S-033447
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Baloxavir.html
Concentration
10mM
Purity
99.75
Solubility
DMSO : 41.67 mg/mL (ultrasonic)
Smiles
O=C1N2[C@](COCC2)([H])N([C@@H]3C4=CC=CC=C4SCC5=C(F)C(F)=CC=C35)N6C1=C(O)C(C=C6)=O
Molecular Formula
C24H19F2N3O4S
Molecular Weight
483.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Omoto S, et al. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep. 2018 Jun 25;8 (1) :9633.|[2]Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Dec;160:109-117.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
Launched

Alternative Products

CatalogName
BA2004-50Baloxavir
RM-B011510-01Baloxavir Impurity 10 (Baloxavir Enantiomer)
B8453-50Baloxavir marboxil
CS-O-41172Baloxavir-D5

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