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Human VEGFR2 protein

CAT: 0013-GTR18881259-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18881259-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This Human VEGFR2 protein spans the amino acid sequence from region 20-764aa. Purity: Greater than 90% as determined by SDS-PAGE.
Product Name Alternative
CD309 protein, CD309 antigen protein, Fetal liver kinase 1 protein, FLK-1 protein, FLK1 protein, FLK1, mouse, homolog of protein, KDR protein, Kinase insert domain receptor (a type III receptor tyrosine kinase) protein, Kinase insert domain receptor protein, KRD1 protein, Ly73 protein, Protein tyrosine kinase receptor FLK1 protein, Protein-tyrosine kinase receptor flk-1 protein, soluble VEGFR2 protein, Tyrosine kinase growth factor receptor protein, Vascular endothelial growth factor receptor 2 protein, VEGFR 2 protein, VEGFR protein, VEGFR-2 protein, VEGFR2 protein
UniProt
P35968
Expression Region
20-764aa
Tag
N-terminal GST-tagged
Source
E.coli
Origin
Homo sapiens (Human)
Field of Research
Cardiovascular Research; Cell Biology
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Molecular Weight
110.3 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes
For research use only.
Applications Notes
Extracellular domain of GST-tag and expression region is 20-764aa
Preservative
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
AA Sequence
ASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGSEQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITENKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQSIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQSGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLE

UniProtKB · P35968

Vascular endothelial growth factor receptor 2

VGFR2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P35968
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
KDR
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
VEGFR-2
EC number
2.7.10.1
Processing
Precursor
Secondary accessions
A2RRS0, B5A925, C5IFA0, O60723, Q14178
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisDifferentiationHost-virus interaction

Ligand

ATP-bindingNucleotide-binding

Cellular component

Cell junctionCell membraneCytoplasmCytoplasmic vesicleEndoplasmic reticulumEndosomeMembraneNucleusSecreted

Molecular function

Developmental proteinKinaseReceptorTransferaseTyrosine-protein kinase

PTM

Disulfide bondGlycoproteinPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainRepeatSignalTransmembraneTransmembrane helix

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