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Human Complement C5 Protein, His Tag

CAT: 0013-GTR18877587-02Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18877587-02Size:100 µg
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Description
Human Complement C5 (w917s), His Tag is expressed from human 293 cells (HEK293) . It contains AA Gln 19 - Cys 1676 (Accession # P01031-1 (W917S) ) .
UniProt
P01031
Expression Region
Gln 19 - Cys 1676
Reactivity
Human
Conjugation
Unconjugated
Tag
C-10xHis
Field of Research
Immunology & Inflammation
Endotoxin
1.0 EU per μg
Purity
95%
Form
Powder
Molecular Weight
73.9 kDa (β chain) & 114.3 kDa (α chain)
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The mature form of Complement C5 is a disulfide-linked heterodimer composed of proteolytically cleaved α and β chain. Each α and β chain has a calculated MW of 73.9 kDa (β chain) and 114.3 kDa (α chain) . The protein migrates as 70 kDa (β chain) and 120-130 kDa (α chain) when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition, and >150 kDa under non-reducing (NR) condition (SDS-PAGE) .
NCBI Accession Number
P01031, W917
Preservative
PBS, pH 7.4

UniProtKB · P01031

Complement C5

CO5_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01031
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
C5
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q14CJ0, Q27I61
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Biological process

Complement alternate pathwayComplement pathwayCytolysisImmunityInflammatory responseInnate immunity

Disease

Disease variant

Cellular component

MembraneMembrane attack complexSecretedTarget cell membraneTarget membrane

Domain

Signal

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