BoNT-IN-1

• Description:

  BoNT-IN-1 is an effective inhibitor of botulinum toxin type A light chain (BoNTA LC), with an IC50 value of 0.9 μM.

• UNSPSC:

  12352005

• Target:

  Antibiotic; Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/BoNT-IN-1.html

• Purity:

  98.35

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC1=C2N=C(C)C=CC2=CC=C1C(NC3=NC=CC(C)=C3)C4=CC=CC=C4[N+]([O-])=O

• Molecular Formula:

  C23H20N4O3

• Molecular Weight:

  400.43

• References & Citations:

  [1]Caglic D, et al. Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain. J Med Chem. 2014 Feb 13;57 (3) :669-676.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [694443-03-3]