(E) -Guggulsterone

(E)-Guggulsterone_x000D_ Catalog number: B2017935_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 1 mg_x000D_ Molecular Weight or Concentration: 312.45_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: 2-8℃_x000D_ Keywords: (17E)-Pregna-4,17(20)-diene-3,16-dione_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Chen WC, Wei CK, Hossen M, Hsu YC, Lee JC. (E)-Guggulsterone Inhibits Dengue Virus Replication by Upregulating Antiviral Interferon Responses through the Induction of Heme Oxygenase-1 Expression Viruses. 2021 Apr 20;13(4):712._x000D_ 2: Shishodia S, Azu N, Rosenzweig JA, Jackson DA. Guggulsterone for Chemoprevention of Cancer Curr Pharm Des. 2016;22(3):294-306._x000D_ 3: Liu T, Bai M, Liu M, Li T, Liao Y, Zhao C, Yao M, Wang J, Wen A, Ding Y. Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-Guggulsterone on ischemic stroke revealed by single-cell transcriptomics Pharmacol Res. 2023 Jul;193:106803._x000D_ 4: Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE 3rd, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS, Darvish-Damavandi M, Mulcahy VL, Kuc RE, Williams TL, Heslop JA, Rossetti D, Tysoe OC, Galanakis V, Vila-Gonzalez M, Crozier TWM, Bargehr J, Sinha S, Upponi SS, Fear C, Swift L, Saeb-Parsy K, Davies SE, Wester A, Hagström H, Melum E, Clements D, Humphreys P, Herriott J, Kijak E, Cox H, Bramwell C, Valentijn A, Illingworth CJR; UK-PBC Consortium; Dahman B, Bastaich DR, Ferreira RD, Marjot T, Barnes E, Moon AM, Barritt AS 4th, Gupta RK, Baker S, Davenport AP, Corbett G, Gorgoulis VG, Buczacki SJA, Lee JH, Matheson NJ, Trauner M, Fisher AJ, Gibbs P, Butler AJ, Watson CJE, Mells GF, Dougan G, Owen A, Lohse AW, Vallier L, Sampaziotis F. FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2 Nature. 2023 Mar;615(7950):134-142._x000D_ 5: Abdellatef AA, Zhou Y, Yamada A, Elmekkawy SA, Kohyama A, Yokoyama S, Meselhy MR, Matsuya Y, Sakurai H, Hayakawa Y. Synthetic E-guggulsterone derivative GSD-1 inhibits NF-κB signaling and suppresses the metastatic potential of breast cancer cells Biomed Pharmacother. 2021 Aug;140:111737._x000D_ 6: Yamada T, Sugimoto K. Guggulsterone and Its Role in Chronic Diseases Adv Exp Med Biol. 2016;929:329-361._x000D_ 7: Ikhlas S, Ahmad M. Binding studies of guggulsterone-E to calf thymus DNA by multi-spectroscopic, calorimetric and molecular docking studies Spectrochim Acta A Mol Biomol Spectrosc. 2018 Feb 5;190:402-408._x000D_ 8: Kweon B, Kim DU, Oh JY, Bae GS, Park SJ. Guggulsterone protects against lipopolysaccharide-induced inflammation and lethal endotoxemia via heme oxygenase-1 Int Immunopharmacol. 2023 Nov;124(Pt B):111073._x000D_ 9: Agrawal H, Kaul N, Paradkar AR, Mahadik KR. HPTLC method for guggulsterone. I. Quantitative determination of E- and Z-guggulsterone in herbal extract and pharmaceutical dosage form J Pharm Biomed Anal. 2004 Sep 21;36(1):33-41._x000D_ 10: Sabarathinam S, Rajappan Chandra SK, Thangavel Mahalingam V. CYP3A4 mediated pharmacokinetics drug interaction potential of Maha-Yogaraj Gugglu and E, Z guggulsterone Sci Rep. 2021 Jan 12;11(1):715. _x000D_ _x000D_ Products Related to (E)-Guggulsterone can be found at Chemicals

Catalog Number: B2017935 (1 mg)

0.15

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0.5