Eflornithine (hydrochloride hydrate) (Standard)

Eflornithine (hydrochloride hydrate) (Standard)

• CAS Number: 96020-91-6
• UNSPSC Description: Eflornithine (hydrochloride hydrate) (Standard) is the analytical standard of Eflornithine (hydrochloride hydrate). This product is intended for research and analytical applications. Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women[1].
• Target Antigen: Parasite
• Type: Reference Standards
• Related Pathways: Anti-infection
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/eflornithine-hydrochloride-hydrate-standard.html
• Smiles: NC(CCCN)(C(F)F)C(O)=O.[H]Cl.O
• Molecular Weight: 236.64
• References & Citations: [1]Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52.|[2]Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2(3):197-201; discussion 202.|[3]Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23(5):1495-501.|[4]Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19(3):297-312.
• Shipping Conditions: Room temperature