Hemin

Hemin

• CAS Number: 16009-13-5
• UNSPSC Description: Hemin is an iron-containing porphyrin. Hemin is an Heme oxygenase (HO)-1 inducer.
• Target Antigen: Autophagy; Ferroptosis; Mitophagy
• Type: Natural Products
• Related Pathways: Apoptosis;Autophagy
• Applications: COVID-19-immunoregulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/Hemin.html
• Purity: 99.53
• Solubility: 1M NaOH : 6.67 mg/mL (ultrasonic;adjust pH to 12 with NaOH)
• Smiles: [Cl-][Fe+3]123[N-]4C5=C(CCC(O)=O)C(C)=C4C=C(C(C=C)=C6C)[N]1=C6C=C(C(C=C)=C7C)[N-]2C7=CC(C(C)=C8CCC(O)=O)=[N]3C8=C5
• Molecular Weight: 651.94
• References & Citations: [1]Vanova K, et al. Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells. BMC Cancer. 2016 May 12;16:309.|[2]Chen HH, et al. Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation. Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2195-201.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched