PIK-108
CAT:
804-HY-111184-02
Size:
100 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PIK-108
- CAS Number: 901398-68-3
- UNSPSC Description: PIK-108 is a non-ATP competitive, allosteric p110β/p110δ selective inhibitor[1].
- Target Antigen: PI3K
- Type: Reference compound
- Related Pathways: PI3K/Akt/mTOR
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pik-108.html
- Purity: 99.05
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C1C=C(N2CCOCC2)OC3=C(C(NC4=CC=CC=C4)C)C=C(C)C=C13
- Molecular Weight: 364.44
- References & Citations: [1]Zachary A Knight, et al. A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. Cell. 2006 May 19;125(4):733-47.|[2]Jack S Chen, et al. Characterization of structurally distinct, isoform-selective phosphoinositide 3'-kinase inhibitors in combination with radiation in the treatment of glioblastoma. Mol Cancer Ther. 2008 Apr;7(4):841-50.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C, 3 years (Powder)
- Clinical Information: No Development Reported