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(S) - (-) -Perillic acid

CAT: 0804-HY-113471A-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113471A-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(S) - (-) -Perillic acid is a terpenoid plant extract with antimicrobial and anticancer activities. (S) - (-) -Perillic acid induces cell apoptosis and cell cycle arrest, and increases the levell of Bax, Bcl2, p21 and caspase-3 proteins. (S) - (-) -Perillic acid can be used for cancer and infection research[1][2][3].
CAS Number
23635-14-5
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Apoptosis; Bacterial
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/s-minus-perillic-acid.html
Purity
95.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(C1=CC[C@@H](C(C)=C)CC1)O
Molecular Formula
C10H14O2
Molecular Weight
166.22
Precautions
H315, H319, H335
References & Citations
[1]Ferri N, et al. Effect of S (-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation. Biochem Pharmacol. 2001 Dec 15;62 (12) :1637-45.|[2]Yeruva L, et al. Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells. Cancer Lett. 2007 Nov 18;257 (2) :216-26.|[3]Khandelia H, et al. Interaction of salicylate and a terpenoid plant extract with model membranes: reconciling experiments and simulations. Biophys J. 2010 Dec 15;99 (12) :3887-94.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported