Products for Research Use Only
RegisterLogin

(R) -IBR2

CAT: 0804-HY-103710ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-103710ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(R) -IBR2 is the isomer of IBR2. IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis[1].
CAS Number
952739-54-7
UNSPSC
12352005
Target
RAD51
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-ibr2.html
Smiles
O=S(N1[C@@H](C2=CNC3=C2C=CC=C3)C4=C(C=CC=C4)C=C1)(CC5=CC=CC=C5)=O
Molecular Formula
C24H20N2O2S
Molecular Weight
400.49
References & Citations
[1]Zhu J, et al. A novel small molecule RAD51 inactivator overcomes imatinib-resistance in chronic myeloid leukaemia. EMBO Mol Med. 2013 Mar;5 (3) :353-65.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-103710-01IBR2
HY-W998245(R, R, R) -AHPC (hydrochloride)
HY-W018061C-01(R, R) -Traxoprodil
HY-103451(R, R) -THC
HY-113834(R, R) -Ethambutol
HY-128888-01(R, R) -GSK321
HY-59125-01(R, R) - (+) -Hydrobenzoin
HY-100443B-01(R, R) -PX20606
HY-B0761(R, R) -Glycopyrrolate
HY-100741C-01(R, R) -S63845

Alternative Products

CatalogName
A19739-25IBR2 25mg
A9000-10IBR2
A19739-50IBR2 50mg
A19739-1IBR2 1mg
A19739-5IBR2 5mg
A19739-200IBR2 200mg
A19739-100IBR2 100mg
A19739-10IBR2 10mg
A19739-10mM-DIBR2 10mM * 1mL in DMSO

Popular Products