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IYPTNGYTR

CAT: 0804-HY-P3147Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P3147Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IYPTNGYTR, a deamidation-sensitive signature peptide, is a deamidation product of Trastuzumab. IYPTNGYTR can be used to monitor in vivo Trastuzumab metabolism[1].
CAS Number
1431957-72-0
UNSPSC
12352209
Target
Drug Metabolite
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/iyptngytr.html
Solubility
H2O
Smiles
O=C(N(CCC1)[C@@H]1C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(NCC(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)CC(C=C2)=CC=C2O)=O)=O)=O)=O)[C@@H](NC([C@@H](N)[C@@H](C)CC)=O)CC(C=C3)=CC=C3O
Molecular Formula
C49H73N13O15
Molecular Weight
1084.18
References & Citations
[1]Bults P, et, al. LC-MS/MS-Based Monitoring of In Vivo Protein Biotransformation: Quantitative Determination of Trastuzumab and Its Deamidation Products in Human Plasma. Anal Chem. 2016 Feb 2;88 (3) :1871-7.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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