Nucleoside-Analog-2

CAT: 0804-HY-77652-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0804-HY-77652-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Nucleoside-Analog-2 is a 4'-Azidocytidine analogue against Hepatitis C virus (HCV) replication. Nucleoside-Analog-2 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
[876708-01-9]
UNSPSC
12352005
Target
HCV; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Nucleoside-Analog-2.html
Purity
95.0
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : 20 mg/mL (ultrasonic)
Smiles
O[C@@H]1[C@](CO)(N=[N+]=[N-])O[C@@H](N2C(NC(C=C2)=O)=O)[C@H]1O
Molecular Formula
C9H11N5O6
Molecular Weight
285.21
References & Citations
[1]Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52 (1) :219-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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