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Pemirolast (potassium)

CAT: 0804-HY-B0538A-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0538A-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pemirolast potassium is an orally active antiallergic agent. Pemirolast potassium attenuates Paclitaxel hypersensitivity reactions. Pemirolast potassium can be used for bronchial asthma and conjunctivitis research[1]-[5].
CAS Number
100299-08-9
Product Name Alternative
TWT-8152; BMY 26517
UNSPSC
12352005
Hazard Statement
H302
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Pemirolast-potassium.html
Purity
99.99
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C1C(C2=N[N-]N=N2)=CN=C3N1C=CC=C3C.[K+]
Molecular Formula
C10H7KN6O
Molecular Weight
266.30
Precautions
H302
References & Citations
[1]Kawashima T, et al. Inhibitory effect of pemirolast, a novel antiallergic drug, on leukotriene C4 and granule protein release from human eosinophils. Int Arch Allergy Immunol. 1994;103 (4) :405-9. |[2]Yanni JM, et al. Comparative effects of topical ocular anti-allergy drugs on human conjunctival mast cells. Ann Allergy Asthma Immunol. 1997 Dec;79 (6) :541-5.|[3]Fujimiya H, et al. Effect of a novel antiallergic drug, pemirolast, on activation of rat peritoneal mast cells: inhibition of exocytotic response and membrane phospholipid turnover. Int Arch Allergy Appl Immunol. 1991;96 (1) :62-7.|[4]Itoh Y, et al. Pemirolast potently attenuates paclitaxel hypersensitivity reactions through inhibition of the release of sensory neuropeptides in rats. Neuropharmacology. 2004 May;46 (6) :888-94. |[5]Tatsushima Y, et al. Pemirolast reduces cisplatin-induced kaolin intake in rats. Eur J Pharmacol. 2011 Jul 1;661 (1-3) :57-62.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H1 Receptor

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