Femoxetine (hydrochloride)

• UNSPSC Description:

  Femoxetine hydrochloride is a serotonin (5-HT) inhibitor with antidepressant properties. Femoxetine hydrochloride increases serotonin levels in the brain by preventing serotonin from being reabsorbed by nerve cells, resulting in increased concentrations of the neurotransmitter in the synaptic gap, which enhances serotonin signaling. Femoxetine hydrochloride can be used to study the role of serotonin in depression and other emotional disorders, and how 5-HT reuptake inhibitors affect mood and behavior[1][2].

• Target Antigen:

  5-HT Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/femoxetine-hydrochloride.html

• Smiles:

  COC(C=C1)=CC=C1OC[C@@H]2[C@@H](C3=CC=CC=C3)CCN(C2)C.Cl

• Molecular Weight:

  347.88

• References & Citations:

  [1]Bechgaard E, et al. Hepatic elimination of femoxetine in pig[J]. Acta Pharmacologica et Toxicologica, 1983, 52(1): 1-7.|[2]Lund J, et al. Pharmacokinetics of femoxetine in man[J]. Acta Pharmacologica et Toxicologica, 1979, 44(3): 177-184.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  56222-04-9