20(S)-Hydroxycholesterol (Standard)

20(S)-Hydroxycholesterol (Standard)

• Product Name Alternative: 20α-Hydroxycholesterol (Standard)
• CAS Number: 516-72-3
• UNSPSC Description: 20(S)-Hydroxycholesterol (Standard) is the analytical standard of 20(S)-Hydroxycholesterol. This product is intended for research and analytical applications. 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells[1][2].
• Target Antigen: Endogenous Metabolite; Smo
• Type: Reference Standards
• Related Pathways: Metabolic Enzyme/Protease;Stem Cell/Wnt
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/20-s-hydroxycholesterol-standard.html
• Purity: 98.69
• Smiles: C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
• Molecular Weight: 402.65
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported