L-739758

CAT: 0804-HY-126039Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-126039Size:1 Each

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Description

L-739758 is an antagonist for αIIbβ3 integrin (platelet glycoprotein IIb/IIIa) . L-739758 acts as a peptidomimetic, binds to αIIbβ3 integrin by mimicking the interaction of the RGD (arginine-glycine-aspartic acid) motif, and is involved in the blood coagulation process. L-739758 inhibits platelet aggregation, and is used for thrombosis research[1].

CAS Number

168157-33-3

UNSPSC

12352005

Target

Integrin

Type

Reference compound

Related Pathways

Cytoskeleton

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-739758.html

Smiles

O=C([C@H](CNC(C1=CC2=C(SC(CCC3CCNCC3)=C2)S1)=O)NS(=O)(C4=CC=CN=C4)=O)O

Molecular Formula

C22H26N4O5S3

Molecular Weight

522.66

References & Citations

[1]Kóňa J. Comparative study of interaction energies between α IIb β 3 integrin and the peptidic, peptidomimetic and non-peptidic ligands by quantum mechanics FMO-PIEDA calculations[J]. Chemical Papers, 2023, 77 (10) : 5913-5930.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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L-739758

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