Gentamicin C1a

CAT: 0804-HY-148286-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-148286-01Size:5 mg
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Description
Gentamicin C1a is the precursor of the semi-synthetic antibiotic Etimicin, and has antibacterial activity. Gentamicin C1a is the major component of the Gentamicin complex[1][2].
CAS Number
[26098-04-4]
UNSPSC
12352005
Hazard Statement
H301, H311, H331, H341
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/gentamicin-c1a.html
Purity
98.0
Solubility
H2O : 250 mg/mL (ultrasonic)
Smiles
O[C@@H]([C@@H]([C@H](C[C@H]1N)N)O[C@H]2O[C@@H](CC[C@H]2N)CN)[C@H]1O[C@@H]3[C@@H]([C@H]([C@@](O)(CO3)C)NC)O
Molecular Formula
C19H39N5O7
Molecular Weight
449.54
Precautions
H301, H311, H331, H341
References & Citations
[1]Li D, et al. Construction of a gentamicin C1a-overproducing strain of Micromonospora purpurea by inactivation of the gacD gene. Microbiol Res. 2013 Jun 12;168 (5) :263-7. |[2]Ishikawa M, et al. Lower ototoxicity and absence of hidden hearing loss point to gentamicin C1a and apramycin as promising antibiotics for clinical use. Sci Rep. 2019 Feb 20;9 (1) :2410. |[3]Isoherranen N, et al. Pharmacokinetics of gentamicin C (1), C (1a), and C (2) in beagles after a single intravenous dose. Antimicrob Agents Chemother. 2000 Jun;44 (6) :1443-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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