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Aluminum Hydroxide

CAT: 0804-HY-B1521-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1521-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines[1][2].
CAS Number
21645-51-2
UNSPSC
12352300
Hazard Statement
H319
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/aluminum-hydroxide.html
Purity
97.0
Solubility
DMSO : < 1 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O[Al](O)O
Molecular Formula
AlH3O3
Molecular Weight
78.00
Precautions
H319
References & Citations
[1]He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11 (2) :477-88.|[2]Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45 (7) :1331-1335.|[3]Ohtawa M, et al. Effect of aluminum ingestion on lipid peroxidation in rats. Chem Pharm Bull (Tokyo) . 1983 Apr;31 (4) :1415-8.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound1
Clinical Information
Launched

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