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Suc-AAPF-pNA

CAT: 0804-HY-P2573-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2573-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Suc-AAPF-pNA (Suc-Ala-Ala-Pro-Phe-pNA) is a chromogenic p-nitroanilide (pNA) substrate with the Km of 1.7 mM. Cleavage of Suc-AAPF-pNA releases 4-nitroaniline, which is yellow in colour and can be measured spectrophotometrically. Suc-AAPF-pNA can be used for the measurement of free and membrane-bound cathepsin G in human neutrophils[1][2][3].
CAS Number
70967-97-4
Product Name Alternative
Suc-Ala-Ala-Pro-Phe-pNA
UNSPSC
12352209
Target
Biochemical Assay Reagents
Type
Peptides
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/suc-aapf-pna.html
Purity
99.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CCC(N[C@@H](C)C(N[C@@H](C)C(N1[C@@H](CCC1)C(N[C@H](C(NC2=CC=C(C=C2)[N+]([O-])=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O
Molecular Formula
C30H36N6O9
Molecular Weight
624.64
References & Citations
[1]Sylvie Attucci, et al. Measurement of free and membrane-bound cathepsin G in human neutrophils using new sensitive fluorogenic substrates. Biochem J. 2002 Sep 15;366 (Pt 3) :965-70.|[2]A J Webb, et al. A protease-based biosensor for the detection of schistosome cercariae. Sci Rep. 2016 Apr 19:6:24725. |[3]Jeanette M Mucha, et al. Enhanced immunogenicity of a functional enzyme by T cell epitope modification. BMC Immunol. 2002:3:2.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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