Products for Research Use Only

TLR Antibody

CAT: 0013-GTR18795153-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18795153-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Anti-TLR7 Antibody is a humanized monoclonal antibody targeting Toll-like receptor 7 (TLR7) . TLR7 is a pattern recognition receptor primarily located on endosomal membranes that recognizes single-stranded RNA (ssRNA), playing a pivotal role in antiviral immune responses and autoimmune diseases such as Systemic Lupus Erythematosus (SLE) . This antibody specifically binds to TLR7, blocking its activation by ligands (e.g., viral RNA or synthetic agonists) and subsequently inhibiting the downstream MyD88-dependent signaling pathway and the production of Type I interferons (IFN-α/β) . By modulating TLR7 signaling, Anti-TLR7 Antibody serves as a valuable tool for investigating viral infection mechanisms and therapeutic strategies for autoimmune disorders.
Target
TLR
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.