D-Ala-D-Ala

D-Ala-D-Ala

• CAS Number: 923-16-0
• UNSPSC Description: D-Ala-D-Ala constitutes the terminus of the peptide part of the peptidoglycan monomer unit and is involved in the transpeptidation reaction as the substrate. D-Ala-D-Ala is catalyzed by D-Alanine-D-Alanine ligase. D-Ala-D-Ala is a bacterial endogenous metabolite[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/d-ala-d-ala.html
• Purity: 97.0
• Solubility: DMSO : 2 mg/mL (ultrasonic;adjust pH to 5 with HCl)|H2O : 100 mg/mL (ultrasonic)
• Smiles: C[C@H](C(O)=O)NC([C@@H](C)N)=O
• Molecular Weight: 160.17
• References & Citations: [1]Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106.|[2]Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported