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Magnesium stearate

CAT: 0804-HY-Y1054-01Size: 500 gDry Ice: NoHazardous: No
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CAT#:0804-HY-Y1054-01Size:500 g
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Description
Magnesium stearate is a commonly used pharmaceutical lubricant. But Magnesium stearate leads to an adverse effect on bonding between particles. Magnesium stearate can be used as an excipient, such as lubricant. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
CAS Number
557-04-0
Product Name Alternative
Stearic Acid Magnesium (II) Salt
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/magnesium-stearate.html
Purity
99.75
Solubility
10 mM in DMSO
Smiles
O=C(CCCCCCCCCCCCCCCCC)O.[Mg].[1/2]
Molecular Formula
C18H36O2·1/2Mg
Molecular Weight
296.64
Precautions
H302, H315, H319, H335
References & Citations
[1]Zuurman K, et al. Effect of magnesium stearate on bonding and porosity expansion of tablets produced from materials with different consolidation properties[J]. International journal of pharmaceutics, 1999, 179 (1) : 107-115.|[2]Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Magnesium Stearate

Magnesium distearate is an organic magnesium salt and a magnesium salt.

CAS Number557-04-0
PubChem CID11177
IUPAC Namemagnesium bis(octadecanoate)
Molecular FormulaC36H70MgO4
Molecular Weight591.2
Topological Polar Surface Area80.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count30
Heavy Atom Count41
Formal Charge0
Complexity196
SMILES
CCCCCCCCCCCCCCCCCC(=O)[O-].CCCCCCCCCCCCCCCCCC(=O)[O-].[Mg+2]
InChI
InChI=1S/2C18H36O2.Mg/c2*1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;/h2*2-17H2,1H3,(H,19,20);/q;;+2/p-2
InChIKey
HQKMJHAJHXVSDF-UHFFFAOYSA-L
Chemical Structure
2D Structure
2D structure of Magnesium Stearate
CAS: 557-04-0
CID: 11177
Formula: C36H70MgO4
MW: 591.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight591.2
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count30
Exact Mass590.5124524
Monoisotopic Mass590.5124524
Topological Polar Surface Area80.3 Ų
Heavy Atom Count41
Formal Charge0
Complexity196
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count3
Compound Is CanonicalizedYes

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