(R)-Carvedilol-d4
CAT:
804-HY-B0006CS-02
Size:
1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

(R)-Carvedilol-d4
- CAS Number: 2747915-92-8
- UNSPSC Description: (R)-Carvedilol-d4 is deuterium labeled (R)-Carvedilol. (R)-Carvedilol ((R)-BM 14190), the R-enantiomer of Carvedilol, is a non-selective β/α-1 blocker. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX)[1].
- Target Antigen: Adrenergic Receptor; Isotope-Labeled Compounds
- Type: Isotope-Labeled Compounds
- Related Pathways: GPCR/G Protein;Neuronal Signaling;Others
- Applications: Neuroscience-Neuromodulation
- Field of Research: Cardiovascular Disease
- Solubility: 10 mM in DMSO
- Smiles: O[C@H](CNC([2H])([2H])C([2H])([2H])OC1=CC=CC=C1OC)COC2=CC=CC(N3)=C2C4=C3C=CC=C4
- Molecular Weight: 410.50
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Wu T, et al. Protective effects of S-carvedilol on doxorubicin-induced damages to human umbilical vein endothelial cells and rats. J Appl Toxicol. 2019 Aug;39(8):1233-1244.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported