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AG01 Antibody

CAT: 0013-GTR18775391-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR18775391-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AG01 is a monoclonal antibody targeting the anti-granular protein precursor (GP88) . It inhibits the proliferation and migration of triple-negative breast cancer (TNBC) cells, reducing the expression of phosphorylated protein kinases such as p-Src, p-AKT, and p-ERK, as well as oncogenic proteins like Axl, c-MET, HIF-1α, and VEGF. In TNBC xenograft mouse models, AG01 suppresses tumor growth and the expression of Ki67 in vivo. AG01 is useful for research involving cancers like TNBC.
Target
HIF/HIF Prolyl-Hydroxylase, Src, Akt, c-Met/HGFR, ERK, VEGFR, TAM Receptor, MMP
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research, Protein Biochemistry, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.

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