Products for Research Use Only

KG-655

CAT: 0804-HY-W012248-01Size: 10 gDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W012248-01Size:10 g
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KG-655 is a small molecule compound that binds to the β-folded surface and internal cavity of ARNT PAS-B and interferes with its binding to the transcriptional coactivator TACC3. KG-655 can promote the homodimerization of ARNT PAS-B and has the potential to regulate multiple ARNT-mediated signaling pathways[1].
CAS Number
349-58-6
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Aryl Hydrocarbon Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/kg-655.html
Purity
99.87
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1
Molecular Formula
C8H4F6O
Molecular Weight
230.11
Precautions
H315, H319, H335
References & Citations
[1]Identification of Small Molecule Ligand Binding Sites On and In the ARNT PAS-B Domain
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported