FX-909

CAT: 0804-HY-153344-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-153344-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARG) inverse agonist. FX-909 can be used for the research of cancer[1].
CAS Number
[2924573-90-8]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fx-909.html
Concentration
10mM
Purity
99.79
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=C2C(NC(C3=C(S(C)(=O)=O)C=CC(C#N)=C3)=CC2=O)=CC(F)=C1
Molecular Formula
C17H10F2N2O3S
Molecular Weight
360.33
References & Citations
[1]Mertz J A, et al. Development of a surrogate tissue pharmacodynamic (PD) assay for clinical use with FX-909, a novel inhibitor of the urothelial luminal lineage transcription factor peroxisome proliferator-activated receptor gamma (PPARG) . Cancer Research, 2023, 83 (7_Supplement) : 2802-2802.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
PPARγ

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