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Rezvilutamide

CAT: 0804-HY-137448-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137448-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rezvilutamide (SHR3680) is an orally active androgen receptor antagonist. Rezvilutamide (SHR3680) is used for the study of prostate cancer[1][2].
CAS Number
1572045-62-5
Product Name Alternative
SHR3680
UNSPSC
12352005
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rezvilutamide.html
Purity
99.76
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
S=C(N(C(C=C1)=CC=C1OC[C@@H](O)CO)C(C)2C)N(C(C=C3)=CC(C(F)(F)F)=C3C#N)C2=O
Molecular Formula
C22H20F3N3O4S
Molecular Weight
479.47
References & Citations
[1]SangjunYoo, et al. New drugs in prostate cancer. Prostate International Volume 4, Issue 2, June 2016, Pages 37-42.|[2]Veronica Mollica, et al. Molecular Mechanisms Related to Hormone Inhibition Resistance in Prostate Cancer. Cells. 2019 Jan 11;8 (1) :43.|[3]Dai T, et al., A single-centre, open-label, single-arm, fixed-sequence pharmacokinetic study of SHR3680 on repaglinide and bupropion in prostate cancer patients. Br J Clin Pharmacol. 2023 Feb;89 (2) :874-886.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

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