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IP3 receptor Rabbit Polyclonal Antibody

CAT: 0013-GTR17744118-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0013-GTR17744118-01Size:50 μL
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Description
IP3 receptor Rabbit Polyclonal Antibody
Product Name Alternative
ACV; CLA4; INSP3R1; IP3R; IP3R1; PPP1R94; SCA15; SCA16; SCA29; D6Pas2; Gm10429; IP3R 1; InsP3R; Itpr-1; P400; Pcp-1; Pcp1; opt; wblo; I145TR; ITPR1_HUMAN; ITPR1; IP3 receptor isoform 1 (IP3R 1 | InsP3R1) ; Inositol 1,4,5 trisphosphate receptor; Inositol 1,4,5-trisphosphate receptor type 1; Type 1 inositol 1,4,5-trisphosphate receptor (Type 1 InsP3 receptor) ; ITPR1_MOUSE; Inositol 1,4,5-trisphosphate-binding protein P400; Protein PCD-6; Purkinje cell protein 1; Pcd6; ITPR1_RAT; Inositol 1,4,5-trisphosphate receptor (IP-3-R) ; spinocerebellar ataxia 15; spinocerebellar ataxia 16; spinocerebellar ataxia 29; inositol 1,4,5-trisphosphate receptor, type 1; protein phosphatase 1, regulatory subunit 94
UniProt
Q14643
Reactivity
Human
Immunogen
KLH conjugated synthetic peptide derived from human IP3R 1 (101-200/2758aa)
Target
ITPR1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Research, Hypoxia, Signal Transduction
Purification
Affinity purified by Protein A
Concentration
1mg/ml
Dilution
ICC/IF=1:100-500, Flow-Cyt=2ug/Test
Form
Liquid
Molecular Weight
314 kDa
References & Citations
Wang, Bin et al. Banxia Xiexin Decoction () Treats Diabetic Gastroparesis through PLC-IP3-Ca2+/NO-cGMP-PKG Signal Pathway Chin J Integr Med, 26, 833-838 (2020)
Pubmed id
32418177
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Prediction Reactivity
Bovine, Canine, Equine, Gallus, Mouse, Porcine, Rabbit, Rat, Sheep
Tested Applications
FC, ICC
Host or Source
Rabbit
Preservative
0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
Isotype
IgG

UniProtKB · Q14643

Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

ITPR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14643
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITPR1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
E7EPX7, E9PDE9, Q14660, Q99897
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisCalcium transportIon transportTransport

Ligand

ATP-bindingCalciumMetal-bindingNucleotide-bindingZinc

Molecular function

Calcium channelIon channelLigand-gated ion channelReceptor

Cellular component

CytoplasmCytoplasmic vesicleEndoplasmic reticulumMembrane

Disease

Disease variantIntellectual disabilityNeurodegenerationSpinocerebellar ataxia

PTM

Disulfide bondGlycoproteinIsopeptide bondLipoproteinPalmitatePhosphoproteinUbl conjugation

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix

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