PFYN peptide

• Description:

  PFYN peptide is a biotin-labled phosphorylated peptide substrate derived from FYN (a Src family kinase) [1].

• UNSPSC:

  12352209

• Target:

  Src

• Type:

  Peptides

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pfyn-peptide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P (O) (O) OC1=CC=C (C=C1) C[C@H] (NC ([C@H] (CCC (O) =O) NC ([C@H] (CC (N) =O) NC ([C@H] (CC (O) =O) NC ([C@H] (CCC (O) =O) NC ([C@H] ([C@@H] (C) CC) NC ([C@H] (CC (C) C) NC ([C@H] (CCCNC (N) =N) NC ([C@H] (C) NC ([C@H] (CC (C) C) NC (CNC (CCCC[C@H]2[C@] ([H]) ([C@] ([H]) (CS2) N3) NC3=O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (C) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCC (N) =O) C (NCC (N[C@@H] (C) C (N[C@@H] (CCCCN) C (N[C@@H] (CC4=CC=CC=C4) C (N5[C@@H] (CCC5) C (N[C@@H] ([C@@H] (C) CC) C (O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O

• Molecular Formula:

  C115H183N32O37PS

• Molecular Weight:

  2668.91

• References & Citations:

  [1]Christofer S Tautermann, et al. Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule. J Med Chem. 2019 Jan 10;62 (1) :306-316.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported