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Kushenol X

CAT: 0804-HY-N3413Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N3413Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Kushenol X, a flavonoid compound isolated from the roots of Sophora flavescens. Kushenol X is a potent β-glucuronidase and human carboxylesterase 2 (hCE2) inhibitor with IC50s of 2.07 μM and 3.05 μM, respectively[1][2].
CAS Number
254886-77-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Carboxylesterase (CES) ; β-glucuronidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kushenol-x.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
CC([C@H](C/C=C(C)/C)CC(C(O)=C1)=C(O[C@H](C(C=CC(O)=C2)=C2O)[C@H]3O)C(C3=O)=C1O)=C
Molecular Formula
C25H28O7
Molecular Weight
440.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Cheng-Peng Sun, et al. The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase. Int J Biol Macromol. 2020 Jan 15;143:349-358.|[2]Sha-Sha Song, et al. Flavonoids as human carboxylesterase 2 inhibitors: Inhibition potentials and molecular docking simulations. Int J Biol Macromol. 2019 Jun 15;131:201-208.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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