PLX7922

CAT: 0804-HY-107415-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-107415-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
PLX7922, a RAF inhibitor, can bind with BRAFV600E. PLX7922 inhibits pERK in BRAFV600E cell lines, and activates pERK in mutant NRAS cell lines[1].
CAS Number
[1638772-61-8]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/plx7922.html
Purity
98.68
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(NC1=C(F)C(C2=C(C3=CC=NC(N)=N3)SC(C(C)(C)C)=N2)=CC=C1)(N(CC)C)=O
Molecular Formula
C20H25FN6O2S2
Molecular Weight
464.58
References & Citations
[1]Zhang C, et, al. RAF inhibitors that evade paradoxical MAPK pathway activation. Nature. 2015 Oct 22;526 (7574) :583-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-18997-01PLX7904
HY-114153-01PLX5622
HY-114153A-01PLX5622 (hemifumarate)
HY-114153CPLX5622 in AIN-76A Diet (1200 ppm)

Alternative Products

CatalogName
BA6537-5PLX7922

Popular Products