Salmeterol-d3

• Description:

  Salmeterol-d3 is a deuterium labeled Salmeterol. Salmeterol is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1].

• UNSPSC:

  12352005

• Target:

  Adrenergic Receptor

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Endocrinology; Inflammation/Immunology

• Purity:

  98.04

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  OC ([2H]) ([2H]) C1=C (O) C=CC (C (CNCCCCCCOCCCCC2=CC=CC=C2) ([2H]) O) =C1

• Molecular Formula:

  C25H34D3NO4

• Molecular Weight:

  418.58

• References & Citations:

  [1]Panayiotis A Procopiou, et al. The discovery of long-acting saligenin β₂ adrenergic receptor agonists incorporating a urea group. Bioorg Med Chem. 2011 Oct 15;19 (20) :6026-32.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• Isoform:

  β adrenergic receptor

• CAS Number:

  497063-94-2