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β-Muricholic acid

CAT: 0804-HY-133707-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-133707-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Muricholic acid is a potent and orally active biliary cholesterol-desaturating agent. β-Muricholic acid prevents cholesterol gallstones. β-Muricholic acid inhibits lipid accumulation. β-Muricholic acid has the potential for the research of nonalcoholic fatty liver disease (NAFLD) [1][2].
CAS Number
2393-59-1
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/β-muricholic-acid.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Formula
C24H40O5
Molecular Weight
408.57
References & Citations
[1]Takada S, et al. Stress can attenuate hepatic lipid accumulation via elevation of hepatic β-muricholic acid levels in mice with nonalcoholic steatohepatitis. Lab Invest. 2021 Feb;101 (2) :193-203.|[2]Wang DQ, et al. Effect of beta-muricholic acid on the prevention and dissolution of cholesterol gallstones in C57L/J mice. J Lipid Res. 2002 Nov;43 (11) :1960-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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