Products for Research Use Only

ANO1 Antibody (CF488)

CAT: 0013-GTR18722990Size: 0.5 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR18722990Size:0.5 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ANO1 Antibody (CF488)
Product Name Alternative
Anoctamin 1, Calcium Activated Chloride Channel, Discovered On Gastrointestinal Stromal Tumors Protein 1, TAOS2, ORAOV2, TMEM16A, DOG1
UniProt
Q5XXA6
Reactivity
Human
Immunogen
Recombinant human DOG-1 protein
Target
ANO1
Clonality
Monoclonal
Clone
DG1/447
Conjugation
CF488
Field of Research
Neuroscience
Purification
Protein G
Concentration
Purified Ab conjugated to CF488
Dilution
Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood) ; Immunofluorescence (1:50-1:100) ; Optimal dilution for a specific application should be determined.
Form
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
Molecular Weight
~114kDa
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Notes
For research use only.
Applications Notes
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin
Tested Applications
FC, IF, IHC
Host or Source
Mouse
Preservative
Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% rAlbumin and 0.05% azide. Contact us if you require this Ab in a different format.
Isotype
IgG1
Entrez
55107

UniProtKB · Q5XXA6

Anoctamin-1

ANO1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5XXA6
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ANO1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A2H4Y9B2, A8KAM3, E9PNA7, Q8IYY8, Q8N7V3
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

CalciumChlorideMetal-binding

Cellular component

Cell membraneCell projectionMembraneSynapse

Molecular function

Chloride channelDevelopmental proteinIon channel

Disease

Disease variant

PTM

Disulfide bondGlycoproteinPhosphoprotein

Biological process

Ion transportTransport

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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