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Mabuterol

CAT: 0804-HY-13338-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-13338-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mabuterol is a selective and orally active beta-2 adrenergic receptor (ADRB2) agonist. Mabuterol inhibits the proliferation and suppresses the increase of intracellular Ca2+ induced by PDGF-BB. Mabuterol suppresses the protein expressions of Drp-1, cyclinD1 and PCNA and enhanced the expression of Mfn-2 induced by PDGF-BB[1][2].
CAS Number
56341-08-3
UNSPSC
12352005
Hazard Statement
H301
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/mabuterol.html
Purity
99.96
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(NCC(O)C1=CC(C(F)(F)F)=C(N)C(Cl)=C1)(C)C
Molecular Formula
C13H18ClF3N2O
Molecular Weight
310.74
Precautions
H301
References & Citations
[1]Yamamoto I, et al. Enzyme immunoassay for mabuterol, a selective beta 2-adrenergic stimulant in the trachea. J Immunoassay. 1985;6 (3) :261-76. |[2]Yaru Gu, et al. Inhibitory effect of mabuterol on proliferation of rat ASMCs induced by PDGF-BB via regulating [Ca2+]i and mitochondrial fission/fusion. Interactions, 2019, 307: 63-72.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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